Bacterial Genetics and Genomics, Chapter 8, Discussion topic 2. As described in Chapter 8 of Bacterial Genetics and Genomics, a two-component regulatory system has a sensory protein in the membrane that autophorphorylates when triggered by its sensory signal and a regulatory protein that is phosphorylated to do its job adjusting gene expression. In this way, somethingContinue reading “What does a two-component regulator do when it isn’t phosphorylated?”
Tag Archives: genes
A single amino acid change can have a big impact on the bacteria.
Bacterial Genetics and Genomics, Chapter 7, Discussion topic 2. It doesn’t take much to alter the sequence of a protein. Whilst some single nucleotide changes to the DNA sequence can be tolerated, others cause the gene to encode a different amino acid in the protein. Again, some of these changes to the amino acid sequence canContinue reading “A single amino acid change can have a big impact on the bacteria.”
Harnessing aptamers for rapid detection of bacteria and antibiotics in our food.
Bacterial Genetics and Genomics book Discussion Topic: Chapter 4, question 14 The specificity of antibody binding has been exploited for many years in a variety of technologies. Although perhaps less famous, aptamers also have high binding specificity for their targets and, being made of RNA or DNA rather than protein, are much smaller in size,Continue reading “Harnessing aptamers for rapid detection of bacteria and antibiotics in our food.”
Research and planning outside of the lab: working with restriction enzymes.
Bacterial Genetics and Genomics book Discussion Topic: Chapter 16, question 15 For this blog, I have decided to look at the Discussion Topic from Bacterial Genetics and Genomics, Chapter 16, question 15, which discusses restriction enzymes and encourages us to try finding digest sites for these enzymes ourselves in a gene of interest, using on-lineContinue reading “Research and planning outside of the lab: working with restriction enzymes.”
Doing research and making discoveries outside of the lab
Investigations in bacterial genetics and genomics using bioinformatics tools can be conducted outside of the lab. This means that so long as you have an internet connection, you can do meaningful research and make meaningful discoveries.
Bacterial Genetics and Genomics, by Lori A. S. Snyder 