Bacterial Genetics and Genomics, Chapter 8, Discussion topic 2. As described in Chapter 8 of Bacterial Genetics and Genomics, a two-component regulatory system has a sensory protein in the membrane that autophorphorylates when triggered by its sensory signal and a regulatory protein that is phosphorylated to do its job adjusting gene expression. In this way, somethingContinue reading “What does a two-component regulator do when it isn’t phosphorylated?”
Tag Archives: genetics
Pathogens at low temperature and antimicrobials.
Bacterial Genetics and Genomics, Chapter 6, Discussion topic 2 and 3. Listeria monocytogenes and Escherichia coli are able to grow at low temperatures and from there be transmitted to humans and cause disease. Having antimicrobials that can work at low temperatures is important to breaking the transmission chain, particularly from food. However, most experiments onContinue reading “Pathogens at low temperature and antimicrobials.”
Regulation of a transcriptional regulator via read-through transcription of an upstream operon.
Bacterial Genetics and Genomics book Discussion Topic: Chapter 5, question 13 The regulation of gene expression means that genes are not ‘on’ all of the time, being transcribed and translated to make protein. The orchestration of gene expression is essential to the processes of the bacterial cell and can involve a number of mechanisms. OftenContinue reading “Regulation of a transcriptional regulator via read-through transcription of an upstream operon.”
Bacterial genomes, then and now
Bacterial Genetics and Genomics book Discussion Topic: Chapter 17, question 13 The publications of the first bacterial genome sequences were 25 years ago. The technology has come a long way since then, both in the lab and computationally. One of the first bacterial genome sequencing projects started was one undertaken to sequence the complete EscherichiaContinue reading “Bacterial genomes, then and now”
Bacterial Genetics and Genomics, by Lori A. S. Snyder 